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(2S,3R)-Voruciclib hydrochloride

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Catalog No. T10096L2
Alias (2S,3R)-Voruciclib hydrochloride (1253731-24-6 free base)

(2S,3R)-Voruciclib hydrochloride is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.

(2S,3R)-Voruciclib hydrochloride

(2S,3R)-Voruciclib hydrochloride

😃Good
Catalog No. T10096L2Alias (2S,3R)-Voruciclib hydrochloride (1253731-24-6 free base)
(2S,3R)-Voruciclib hydrochloride is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.
Pack SizePriceAvailabilityQuantity
5 mg$311Backorder
10 mg$486Backorder
50 mg$1,454Backorder
100 mg$1,981Backorder
200 mgInquiryBackorder
500 mgInquiryBackorder
1 mL x 10 mM (in DMSO)$346Backorder
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Product Introduction

Bioactivity
Description
(2S,3R)-Voruciclib hydrochloride is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.
In vitro
(2S,3R)-Voruciclib (Compound B, formula I) is used in combination with a compound capable of inhibiting EGFR kinase activity and Gemcitabine to treat pancreatic cancer.
Alias(2S,3R)-Voruciclib hydrochloride (1253731-24-6 free base)
Chemical Properties
Molecular Weight506.3
FormulaC22H20Cl2F3NO5
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 250 mg/mL (493.78 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9751 mL9.8756 mL19.7511 mL98.7557 mL
5 mM0.3950 mL1.9751 mL3.9502 mL19.7511 mL
10 mM0.1975 mL0.9876 mL1.9751 mL9.8756 mL
20 mM0.0988 mL0.4938 mL0.9876 mL4.9378 mL
50 mM0.0395 mL0.1975 mL0.3950 mL1.9751 mL
100 mM0.0198 mL0.0988 mL0.1975 mL0.9876 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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